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Synthesis of deuterium labeled standards of 5-methoxy-N,N-dimethyltryptamine (5-Meo-DMT)

✍ Scribed by Ya-Zhu Xu; Chinpiao Chen

Publisher
John Wiley and Sons
Year
2006
Tongue
French
Weight
108 KB
Volume
49
Category
Article
ISSN
0022-2135

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✦ Synopsis

The Batcho-Leimgruber strategy was employed to synthesize 5-[ 2 H 3 ]-methoxy-1 H-indole 4 from commercially available 5-hydroxy-2-nitrotoluene 1 and CD 3 I. Compound 4 was treated with oxalyl chloride, dimethylamine and lithium aluminum hydride to yield 5-[ 2 H 3 ]-methoxy-N,N-dimethyltryptamine 6.

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