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Synthesis of deuterated and tritiated derivatives of enflurane

✍ Scribed by Terrence R. Burke Jr.; Lance R. Pohl

Publisher: John Wiley and Sons
Year: 1981
Tongue: French
Weight: 296 KB
Volume: 18
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580180507

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✦ Synopsis

Abstract

Specifically deuterated derivatives of the inhalation anesthetic enflurane [2‐chloro‐1‐(difluoromethoxy)‐1,1,2‐trifluoroethane] have been synthesized by a facile base catalyzed exchange. Tritiated enflurane has also been synthesized by this procedure.

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