Synthesis of derivatives of a new heterocyclic system, 9-oxo-1,3,4-thiadiazolo[3,2-a]pyrido[3,2-e]pyrimidine
✍ Scribed by S. Sh. Shukurov; M. A. Kukaniev; M. I. Nasyrov
- Book ID
- 112388712
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 202 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1573-9171
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## Abstract 2‐Alkyl‐, 2‐aryl‐, and 2‐halo‐substituted derivatives of 7‐methyl‐6‐fluoro‐1,3,4‐thiadiazolo[3,2‐__a__]pyrimidin‐6‐one (**3**) were prepared by reaction of 2‐substituted 5‐amino‐1,3,4‐thiadiazoles (**1**) and ethyl 2‐fluoroacetoacetate (**2**) in polyphosphoric acid. A convenient proced
## Abstract 2‐Alkyl and 2‐arylhydrazine derivatives of 5__H__‐2‐R‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo[3,2‐__a__]pyrimidin‐5‐one were prepared by reaction of 5__H__‐2‐bromo‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo[3,2‐__a__]pyrimidin‐5‐one with hydrazine derivatives. A convenient procedure was developed