Synthesis of dehydroepiandrosterone sulfatide and 16α-Halogenated steroids
✍ Scribed by Magid Abou-Gharbia; Laura Pashko; Arthur Schwartz; Daniel Swern
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 473 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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## Incubation of 6u-fluoro-Reichstein's Compound 3'" (I) and its A'-analog (IV) with bovine adrenals followed by acetylation led to 6c4uorohydrocortisone acetate (II) and 6a-fluoroprednisolone acetate (III) respectively. Selenium dioxide oxidation of II also afforded III. Chromium trioxide oxidati