✦ LIBER ✦

Synthesis of cyclohexanone-based cathepsin B inhibitors that interact with both the S and S′ binding sites

✍ Scribed by Jeffrey L. Conroy; Paul Abato; Mousumi Ghosh; Mariana I. Austermuhle; Michael R. Kiefer; Christopher T. Seto

Book ID: 108387090
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 242 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)01783-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Cycloh

ChemInform Abstract: Synthesis of Cyclohexanone-Based Cathepsin B Inhibitors That Interact with Both the S and S′ Binding Sites.

✍ J. L. CONROY; P. ABATO; M. GHOSH; M. I. AUSTERMUHLE; M. R. KIEFER; C. T. SETO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Inhibitors of Plasmin that Extend into B

Inhibitors of Plasmin that Extend into Both the S and S‘ Binding Sites: Cooperative Interactions between S1 and S2

✍ Abato, Paul; Yuen, Courtney M.; Cubanski, Jeanne Y.; Seto, Christopher T. 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 135 KB

Binding Characteristics and Interactions

Binding Characteristics and Interactions of Depressant Drugs with [35S]t-Butylbicyclophosphorothionate, a Ligand that Binds to the Picrotoxinin Site

✍ R. Ramanjaneyulu; M. K. Ticku 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 899 KB

Variants of the Antibody Herceptin That

Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site

✍ Bostrom, J.; Yu, S.-F.; Kan, D.; Appleton, B. A.; Lee, C. V.; Billeci, K.; Man, 📂 Article 📅 2009 🏛 American Association for the Advancement of Scienc 🌐 English ⚖ 508 KB

The Gabriel-Colman rearrangement in biol

The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3

✍ William C. Groutas; Lee S. Chong; Radhika Venkataraman; Jeffrey B. Epp; Rongze K 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 574 KB

Almtraet--The results of a structure-activity relationship study focusing on the interaction of a series of phthalimide and saccharin derivatives with leukocyte elastase, cathepsin G and proteinase 3 are described. The phthalimide derivatives were found to be inactive while some of the saccharin der

95 Real-time characterization of the int

95 Real-time characterization of the interaction of HIV-1-specific inhibitors with their binding site at the HIV-1 reverse transcriptase (RT) using surface plasmon resonance and biosensor technology: R. Pauwels1, B. Persson2, L.G. Fägerstam2, L. Öfås2, K. De Vreese1 P. Van Daele3, Z. Debyser1, R. Bhikhabhai4, B. Strandberg4, J. Desmyter1, P.A.J. Janssen3 and E. De Clercq1 1Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium; 2Pharmacia Biosensor AB, Uppsala, Sweden; 3Janssen Research Foundation, Beerse, Belgium; and 4Institute of Molecular Biology, Uppsala University, Uppsala, Sweden

📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 92 KB