Synthesis of conformationally restricted sulfonamides via radical cyclisation
β Scribed by D. Biswas; L. Samp; A.K. Ganguly
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 671 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Alcohols bearing suitable chains for radical initiation are smoothly condensed with cyclic Pdiketones to afford systems which undergo radical cyclisation to give various spircether products.
The Michael type addition of vinyl radicals on to the enone double bond was realised in Wieland-Miescher ketone derivatives leading to the formation of functionalised propellanes.
Synthesis of compounds structurally related to morphine is a field of lasting interest to many chemists. These substances form a well-known class of analgesics2 which can possess properties of antagonism to narcotics3 and which includes phenazocine4 and pentazocine5 of medicinal use. The Grewe synth