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Synthesis of Conformationally Locked Versions of Puromycin Analogues

✍ Scribed by Saneyoshi, Hisao; Michel, Benoît Y.; Choi, Yongseok; Strazewski, Peter; Marquez, Victor E.


Book ID
111949799
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
188 KB
Volume
73
Category
Article
ISSN
0022-3263

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Total Syntheses of a Conformationally Lo
✍ Benoît Y. Michel; Peter Strazewski 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 485 KB

## Abstract **Locked in translation**: Crucial insight into the ribosomal catalysis of peptide‐bond formation is expected to be gained from the target compounds, which feature conformational locking in a __North‐__type pucker, designed to interfere with the translation of the genetic code. The comp