๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of a Conformationally Locked Version of Puromycin Amino Nucleoside

โœ Scribed by Choi, Yongseok; George, Clifford; Strazewski, Peter; Marquez, Victor E.


Book ID
118146148
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
52 KB
Volume
4
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Conformationally locked nucleosides. Syn
โœ Guangyi Wang ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 226 KB

3'-Amino-3'-deoxythymidine was converted, in multi-steps, to its 5'-O-(4,4'-dimethoxytrityl)-5'-C-tosyloxyethyl-3'-N-carbobenzoxy derivative 7 and 5'-C-mesyloxyethyl-3'-N-(9-fluorenyl)methoxycarbonyl derivatives 6 and 11. Subsequent hydrogenolysis or treatment with DMAP afforded 3'-N,5'-C-bridged bi

Total Syntheses of a Conformationally Lo
โœ Benoรฎtโ€…Y. Michel; Peter Strazewski ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 485 KB

## Abstract **Locked in translation**: Crucial insight into the ribosomal catalysis of peptideโ€bond formation is expected to be gained from the target compounds, which feature conformational locking in a __Northโ€__type pucker, designed to interfere with the translation of the genetic code. The comp