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Synthesis of Conformationally Constrained Lysine Analogues

✍ Scribed by Ganorkar, Rakesh; Natarajan, Amarnath; Mamai, Ahmed; Madalengoitia, José S.


Book ID
127393871
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
102 KB
Volume
71
Category
Article
ISSN
0022-3263

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Synthesis of conformationally constraine
✍ Hideki Abe; Yumiko Arai; Sakae Aoyagi; Chihiro Kibayashi 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 99 KB

Conformationally constrained spirofuropyridine analogues of epibatidine, syn-2 and anti-2, in which the 7-azabicyclo[2.2.1]heptane system and the 2-chloropyridine ring are held rigidly with the shorter and longer N-N distances, respectively, were synthesized from N-Boc-7-azabicyclo[2.2.1]heptan-2-on