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Synthesis of Coenzymically Active Soluble and Insoluble Macromolecularized NAD+ Derivatives

✍ Scribed by Piergiorgio ZAPPELLI; Antonio ROSSODIVITA; Luciano RE

Book ID
115115014
Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
730 KB
Volume
54
Category
Article
ISSN
1432-1327

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✍ Gianconno Carrea; Gianluca Ottolina; Sergio Riva; Bruno Danieli; Giordano Lesma; πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 German βš– 727 KB

The reactivity of 1,3-propanesultone with adenine, adenosine, and NAD+ was studied in order to prepare N6-(3-sulfonatopropy1)-NAD+ (3b), a new NAD' derivative substituted at the purine moiety with substantial coenzyme activity for several dehydrogenases. The regiochemistry of the alkylation at the p