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New Coenzymically-Active Soluble and Insoluble Macromolecular NAD + Derivatives

✍ Scribed by Piergiorgio ZAPPELLI; Antonio ROSSODIVITA; Giulio PROSPERI; Rosario PAPPA; RE Luciano

Book ID
115115194
Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
496 KB
Volume
62
Category
Article
ISSN
1432-1327

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πŸ“œ SIMILAR VOLUMES

Alkylation of Adenine, Adenosine, and NA
Alkylation of Adenine, Adenosine, and NAD+ with 1,3-Propanesultone. Synthesis of N6-(3-sulfonatopropyl)-NAD+, a new NAD+ derivative with substantial coenzyme activity
✍ Gianconno Carrea; Gianluca Ottolina; Sergio Riva; Bruno Danieli; Giordano Lesma; πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 German βš– 727 KB

The reactivity of 1,3-propanesultone with adenine, adenosine, and NAD+ was studied in order to prepare N6-(3-sulfonatopropy1)-NAD+ (3b), a new NAD' derivative substituted at the purine moiety with substantial coenzyme activity for several dehydrogenases. The regiochemistry of the alkylation at the p