Synthesis of chiral N-aryl-α-amino acids by PdCu catalyzed couplings of chiral α-amino acids with aryl halides
✍ Scribed by Dawei Ma; Jiangchao Yao
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 199 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
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We have developed an efficient method for the preparation of enantiopure N-aryl-a-amino acids via copper-catalyzed N-arylation of a-amino acids and aryl halides under microwave irradiation. This protocol only needs less than 30 min to obtain the products, which are far superior to those obtained und
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