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Copper-catalyzed C–N coupling reactions of aryl halides with α-amino acids under focused microwave irradiation

✍ Scribed by Nasani Narendar; Sivan Velmathi

Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
186 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis

We have developed an efficient method for the preparation of enantiopure N-aryl-a-amino acids via copper-catalyzed N-arylation of a-amino acids and aryl halides under microwave irradiation. This protocol only needs less than 30 min to obtain the products, which are far superior to those obtained under conventional heating.

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