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Synthesis of cell-wall analogues of vancomycin-resistant enterococci using solid phase peptide synthesis

✍ Scribed by Younghoon R. Cho; Richard M.H. Entress; Dudley H. Williams

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 238 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)01110-6

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✦ Synopsis

A convenicn! melht~ for tile dirccl coupling of lithium D-lactate Io 2-chlorotrityl chloride resin enabled the rapid and efficient solid phase synthesis of bacteri~d cell-wall precursor analogues (depsipeptides) fimnd in vancomycin-resistant culcrococci (VRE).

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