𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of carboranyl derivatives of alkynyl glycosides as potential BNCT agents

✍ Scribed by Giovanni Battista Giovenzana; Luigi Lay; Diego Monti; Giovanni Palmisano; Luigi Panza


Book ID
104209720
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
666 KB
Volume
55
Category
Article
ISSN
0040-4020

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✦ Synopsis


A series of amphiphilic carbohydrate-carborane hybrids consisting of a lipophilic core (carborane cage) and a glycoside moiety for conferring high-affinity recognition by the cellular lectins have been prepared in a chemically accessible fashion.


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Synthesis of Ξ±-carboranyl-Ξ±-acyloxy-amid
✍ Subash C. Jonnalagadda; Jonathan S. Cruz; Ryan J. Connell; Patricia M. Scott; Ve πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 757 KB

Novel Ξ±-carboranyl-Ξ±-acyloxy-amides were prepared as potential BNCT agents utilizing three component Passerini reaction. Preliminary cytotoxicity of the representative compounds on two brain tumor cell lines (U-87 and A-172) showed no effect on cell viability; an essential requirement for utility as