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Synthesis of carbon-14 labeled dibutyltin dichloride

✍ Scribed by Anita Lewin; Robert Jeffcoat; Bertold Berrang

Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
100 KB
Volume
50
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

This report describes the preparation of carbon‐14 labeled dibutyltin dichloride from carbon‐14 labeled barium carbonate in 30% overall radiochemical yield. The key steps were (a) the preparation of carbon‐14 labeled butyl bromide from carbon‐14 labeled barium carbonate via carbon‐14 labeled butyl mesylate, and (b) the direct preparation of tetrabutyltin by the lithium‐mediated reaction of dibutyltin dichloride with carbon‐14 labeled butyl bromide. Copyright © 2007 John Wiley & Sons, Ltd.

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