## Abstract 1‐Ethyl‐6‐fluoro‐1,4‐dihydro‐4‐oxo‐7‐(1‐piperazinyl)‐ 3‐quinolinecarboxylic acid (__I__, AM‐715), a new potent antibacterial agent, was labelled with carbon‐14 at the C‐1 position of the N‐ethyl group for metabolic studies. The synthesis was achieved according to two reaction routes. Th
Synthesis of carbon-14 labeled 1-(4-methoxybenzoyl)-5-oxo-2-pyrrolidinepropanoic acid (CI-933)
✍ Scribed by C. C. Huang
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- French
- Weight
- 260 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Phenyl-piperazinomethyl-amino-oxazoline 3. labelled with carbon-14 was obtained in good yield in two steps from [14CIepichlorhydrin. Specific radioactivity: 19.40 PCilmg; 5,09 mCilmmo1. Radiochemical yield: 50 % of the theoretical amount.
## Abstract The synthesis of ^14^C‐labelled __cis__‐malonato[(4__R__,5__R__)‐4,5‐bis(aminomethyl)‐2‐isopropyl‐1,3‐dioxolane]platinum(II) from [1,4‐^14^C] D‐tartaric acid is described. The overall radiochemical yield of the product in a eight‐step sequence was 23.8% and radiochemical purity was 98.5
## Abstract 1,4‐Dihydro‐1‐methoxy‐6,7‐methylenedioxy‐4‐oxoquinoline‐3‐carboxylic acid (I) (AB‐206), a new synthetic antimicrobial agent, was labelled with carbon‐14 at C‐3 position of the quinolinone ring for metabolic studies. The synthesis was achieved according to the reaction schemes shown in F
## Abstract 5‐Methoxy‐2‐methyl‐1‐(3,4‐methylenedioxybenzoyl)indole‐3‐acetic acid (ID‐955)(I), a new anti‐inflammatory agent, was labelled with carbon‐14 at C‐2 position of indole nucleus for the use of metabolic studies. The procedure used is shown in Fig. 1 and 2. Levulinic‐4‐^14^C acid was synthe
S W 86002, 6-(4-f luorophenyl) -5-(4-pyridyl) -2,3-dihydroimidazo[2,l-b] thiazole, was synthesized labeled pith carbon-14 at C-1 or 14-2,3 using either [ C] thiourea or 1,2-dibromo [ C 3 ethane, respectively. The synthetic route, invogving the condensation of an asymmetric benzoin with thiourea foll