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Synthesis of C-8 methanesulphonate substituted pyrrolobenzodiazepines as potential antitumour agents

✍ Scribed by Ahmed Kamal; P Ramulu; O Srinivas; G Ramesh

Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 125 KB
Volume: 13
Category: Article
ISSN: 0960-894X
DOI: 10.1016/s0960-894x(03)00738-8

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✦ Synopsis

The facile synthesis of C-8 methanesulphonate substituted pyrrolobenzodiazepines is described. These have been prepared by linking the methanesulphonate at C-8 position with alkanol spacer and their in vitro cytotoxicity have been described.

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