Synthesis of C-5-thioglycopyranosides and their sulfonium derivatives from 1-C-(2′-oxoalkyl)-5-S-acetylglycofuranosides
✍ Scribed by Tian Yi; Shih-Hsiung Wu; Wei Zou
- Book ID
- 108080193
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 371 KB
- Volume
- 340
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
transfer reaction fmm (-)-or (+)-[2-'H,]-isobomyloxymagnesium bmmide to a 5-oxoribose derivative., which can be readily prepared hum ['3C,]-D-glucose. The overall yield from D-glucose to thymidine wig 27%. The various nucleosides with tt stereoselective 'H-label together with "C at the C5' position,
SYNTHESIS OF (2s , 4S)-[5-l 3C] LEUC INE , (2R ,4S)-[5-' 3C] LEUC I NE , AND (2RS)-[1 ,2-13C,] LEUCINE D. John Aberhart\* and Bruce H. W e i l l e r The Worcester Foundation f o r Experimental B i o l o g y Shrewsbury, Massachusetts 01545 SUMMARY (2RSY3S)-[4-13 ClVal i n e was d i a z o t i z e d an
Three selectively labeled propynes were prepared either with deuterium or carbon-13 at position 3 and doubly labeled with carbon-13 at positions 1 and 2 by an alkylation reaction from the corresponding labeled or unlabeled monolithio acetylides and dimethylsulfates. Their lithiation with nBuLi gave