✦ LIBER ✦

Synthesis of bis-heteroaryl piperazine derivatives as potential reverse transcriptase inhibitors

✍ Scribed by Jean Guillaumel; David S. Grierson; Claude Monneret

Book ID: 102345226
Publisher: Journal of Heterocyclic Chemistry
Year: 2001
Tongue: English
Weight: 37 KB
Volume: 38
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570380429

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Vinylogous analogs of non‐nucleoside reverse transcriptase inhibitors belonging to the bis‐(hetero‐aryl)piperazine (BHAP) series were synthesized by coupling a piperazine derivative with (E)‐propenoyl derivatives of heterocyclic moieties.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Bis-he

ChemInform Abstract: Synthesis of Bis-heteroaryl Piperazine Derivatives as Potential Reverse Transcriptase Inhibitors.

✍ Jean Guillaumel; David S. Grierson; Claude Monneret 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Design and synthesis of a conformational

Design and synthesis of a conformationally constrained analog of the bis(heteroaryl)piperazine (BHAP) HIV-1 reverse transcriptase inhibitor atevirdine

✍ Michael J. Genin; Constance G. Chidester; Douglas C. Rohrer; Donna L. Romero 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 350 KB

Spectroscopic studies of delavirdine mes

Spectroscopic studies of delavirdine mesylate (U-90,152T) a bis(heteroaryl)piperazine (BHAP) HIV reverse transcriptase inhibitor

✍ Kathleen A. Farley; Gregory S. Walker; Russell H. Robins; Jane E. Kupstas-Guido; 📂 Article 📅 1996 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 294 KB

Synthesis of Novel Uracil Non-Nucleoside

Synthesis of Novel Uracil Non-Nucleoside Derivatives as Potential Reverse Transcriptase Inhibitors of HIV-1

✍ Nasser R. El-Brollosy; Omar. A. Al-Deeb; Ali A. El-Emam; Erik B. Pedersen; Paolo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 407 KB 👁 2 views

Targeting Delavirdine/Atevirdine Resista

Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors

✍ Romero, Donna L.; Olmsted, Robert A.; Poel, Toni Jo; Morge, Raymond A.; Biles, C 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 617 KB

Synthesis and Bioactivity of Novel Bis(h

Synthesis and Bioactivity of Novel Bis(heteroaryl)piperazine (BHAP) Reverse Transcriptase Inhibitors: Structure−Activity Relationships and Increased Metabolic Stability of Novel Substituted Pyridine Analogs

✍ Genin, Michael J.; Poel, Toni J.; Yagi, Yoshihiko; Biles, Carolyn; Althaus, Iren 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 279 KB