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Synthesis of bifunctionalized nitroxyls via intramolecular epoxide ring opening

✍ Scribed by Olga A Ozhogina

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
72 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

The syntheses of nitroxyl oxirane and further functionalized derivatives are described. Ring-cleavage reactions of this epoxide have been carried out with a variety of nucleophiles in order to show the general synthetic utility for preparing nitroxyls bearing two functional groups. The relatively facile synthesis of the nitroxyl amino alcohol should prove to be valuable in various spin labeling applications.

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