An efficient formal synthesis of balanol is described. The thirteen-step sequence features a highly enantioselective (92% ee) ring opening of 1,4-cyclohexadiane monoepoxide with TMSN~ catalyzed by the Cr-salen complex 3. A selective Beckmann rearrangement followed by amide reduction and nitrogen fun
An Epoxide Ring-Opening Reaction via Hypervalent Silicate Intermediate: Synthesis of Statine.
β Scribed by Hiroyuki Konno; Emi Toshiro; Naoyuki Hinoda
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 168 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A novel tandem one-pot method for the synthesis of a-aminomethylene-c-butyrolactone derivatives has been developed through the regioselective epoxide opening reactions with the Blaise reaction intermediates, generated by the reaction of a Reformatsky reagent with nitriles. Formation of a modified Bl
## Abstract The reaction of the Reformatsky reagent derived from ethyl bromoacetate and subsequent coupling of the resulting Blaise intermediate with oxiranes allows the synthesis of the title compounds in fair yields.
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v