Synthesis of Bicyclic Peptides
β Scribed by Tuomas Karskela; Pasi Virta; Harri Lonnberg
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 11 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
The solid-phase synthesis and characterization of a series of accomplished by means of diisopropylcarbodiimide (DIC)/ hydroxyazabenzotriazole (HOAt). Coupling between amino peptides (4-15) containing reverse-turn mimetic bicyclic lactams is reported. The bicyclic lactams (1a, 1b) possess acids and t
The ion binding characteristics of two bicyclic peptides, cyclo(Lys-Pro-Gly-Pro-Gly-Glu-Pro-Gly-Pro-G1y)-cyclo(1c + 6 y ) Gly (BCP7) and cyclo(Lys-Pro-Gly-Pro-Gly-Glu-Pro-Gly-Pro-G1y)qclo(lr + 6 y ) Gly-Gly (BCP8) in a lipophilic solvent, acetonitrile, have been studied using CD and nmr spectroscopy