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Solid-Supported Synthesis of Bicyclic Peptides Containing Three Parallel Peptide Chains

✍ Scribed by Tuomas Karskela; Petri Heinonen; Pasi Virta; Harri Lönnberg

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
122 KB
Volume
2003
Category
Article
ISSN
1434-193X

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✍ Cesare Gennari; Antonia Mielgo; Donatella Potenza; Carlo Scolastico; Umberto Pia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 2 views

The solid-phase synthesis and characterization of a series of accomplished by means of diisopropylcarbodiimide (DIC)/ hydroxyazabenzotriazole (HOAt). Coupling between amino peptides (4-15) containing reverse-turn mimetic bicyclic lactams is reported. The bicyclic lactams (1a, 1b) possess acids and t