Synthesis of benzocycloheptene-based amino acid derivatives via a [4+2] cycloaddition reaction as a key step
✍ Scribed by Sambasivarao Kotha; Nampally Sreenivasachary; Enugurthi Brahmachary
- Book ID
- 108371274
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 101 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0040-4020
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## Abstract The diazonium salt of 2‐aminophenol **2** was coupled __in situ__ with malononitrile derivatives **3a‐d**, 2‐cyanomethylthiazolin‐4‐one **9**, 2‐cyanomethylbenzimidazole **11a**, and 2‐cyanomethylbenzothiazole **11b** to give 2‐amino[1,4,5]benzoxadiazepine derivatives **6a‐d, 10** and *