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Synthesis of aryl ethers from aminoalcohols using polymer-supported triphenylphosphine

โœ Scribed by Mike E. Lizarzaburu; Stephen J. Shuttleworth

Book ID
104250646
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
115 KB
Volume
43
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Optimum conditions for the preparation of aryl-alkyl ethers from N-protected aminoalcohols using polymer-supported triphenylphosphine have been developed. In contrast to previous literature reports, it was discovered that the progress of this reaction is greatly improved when a tertiary amine base is employed, along with minor modifications being made to the order of reagent addition.

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