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Polymer supported bases in combinatorial chemistry: Synthesis of aryl ethers from phenols and alkyl halides and aryl halides

โœ Scribed by Wei Xu; Raju Mohan; Michael M. Morrissey


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
215 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Polymer supported 1,

5,

.0]dec-5-ene (PTBD) was used as a base and a reagent scavenger for rapid synthesis of aryl ethers from phenols and alkyl or aryl halides. This method provides a simple reaction operation, and generally high purity of reaction product in good yield.


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Polymer-bound triphenylphosphine as trac
โœ Ashok Rao Tunoori; Dinah Dutta; Gunda I. Georg ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 202 KB

The synthesis of aryl ethers from phenols and alcohols using polymer-bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the prod