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Synthesis of aromatic derivatives of 1,5-benzodiazepine in the reaction of 4-nitro-o-phenylenediamine with chalcone dibromides

โœ Scribed by N. N. Kolos; V. D. Orlov; E. Ya. Yuzefovskaya; F. G. Yaremenko; N. P. Vorob'eva; O. V. Shishkin; Yu. T. Struchkov; S. M. Ivkov


Publisher
Springer US
Year
1995
Tongue
English
Weight
693 KB
Volume
31
Category
Article
ISSN
0009-3122

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## 1,5-benzodiazepines / Cyclizations / Cycloadditions The reaction of o-phenylenediamine (4) with one, two or three equivalents of p-substituted 3-dimethylaminopropiophenone hydrochlorides 5a-e was studied. 4-Aryl-2,3-dihydro-1H-1,5-benzodiazepine derivatives 6a-e were obtained in good yields, alo