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Enantioselective Synthesis of 2-Substituted-1,5-Benzodiazepines through Domino Reaction of o-Phenylenediamine and Chalcone Derivatives

โœ Scribed by Xuan Fu; Juhua Feng; Zhenhua Dong; Lili Lin; Xiaohua Liu; Xiaoming Feng


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
216 KB
Volume
2011
Category
Article
ISSN
1434-193X

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โœ Braulio Insuasty; Rodrigo Abonia; Jairo Quiroga; Angela Salcedo; Heinz Kolshorn; ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 252 KB ๐Ÿ‘ 1 views

## 1,5-benzodiazepines / Cyclizations / Cycloadditions The reaction of o-phenylenediamine (4) with one, two or three equivalents of p-substituted 3-dimethylaminopropiophenone hydrochlorides 5a-e was studied. 4-Aryl-2,3-dihydro-1H-1,5-benzodiazepine derivatives 6a-e were obtained in good yields, alo