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Synthesis of Annelated Azaheterocycles Containing a 5-Carbamoylpyrazin-3-one Fragment by a Modification of the Four-Component Ugi Reaction.

✍ Scribed by Alexey P. Ilyin; Vladimir V. Kobak; Irina G. Dmitrieva; Yulia N. Peregudova; Veronika A. Kustova; Yulia S. Mishunina; Sergey E. Tkachenko; Alexandre V. Ivachtchenko


Publisher
John Wiley and Sons
Year
2006
Weight
40 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract Alkyl 2‐nitroethanoates react with alkyl propiolates in the presence of triphenylphosphine (Ph~3~P) in a mechanistically unprecedented reaction to afford tetraalkyl benzene‐1,2,3,5‐tetracarboxylates in moderate yields (36–42%).