Studies on Isocyanides. A Facile Synthesis of 4,5-Dihydro-1,4-benzothiazepin-3(2H)-ones via Post-Condensation Modifications of the Ugi Reaction.
β Scribed by Ana G. Neo; Carlos F. Marcos; Stefano Marcaccini; Roberto Pepino
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 21 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract For Abstract see ChemInform Abstract in Full Text.
5(4H)-ones / 2-Chloro-N-cyanomethyl-N-methylnicotinamide / Aromatic nucleophilic substitution A new synthesis of pyrido[3,2-f][1,4]thiazepine derivatives 3 starting with 2-chloronicotinic acid (1), methylaminoacetonitrile hydrochloride and carbon disulfide is described. As proved by a crystal struct