Synthesis of 7,8-Dihydrothieno[3′,2′:4,5]pyrrolo[1,2-a]pyrazin-5(6H)-ones Using a Modification of Four-Component Ugi Reaction.
✍ Scribed by Alexey P. Ilyin; Vladimir V. Kobak; Irina G. Dmitrieva; Yulia N. Peregudova; Veronika A. Kustova; Yulia S. Mishunina; Sergey E. Tkachenko; Alexandre V. Ivachtchenko
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 20 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The aza‐Wittig reactions of benzophenone‐, acetophenone‐ and benzaldehyde l‐[(triphenylphosphoranyl‐idene)amino]ethylidenehydrazones (4) with phthalic anhydride, 2,3‐dimethylmaleic anhydride and 7‐oxabi‐cyclo[2,2,l]hept‐5‐ene‐2,3‐dicarboxylic anhydride (**5a**) provide a new route to 5_
## Abstract Fused tricyclic 7‐phenyl‐5__H__‐thizolo[5,4‐__e__]pyrrolo[1,2‐__a__][1,4]diazepin‐10(9__H__)one (**10**) was prepared by thermolysis of 2‐phenyl‐4‐(1‐pyrrolylmethyl)thiazole‐5‐carbonyl azide (**9**) in acetic acid. In addition, starting from **10**, 7‐phenyl‐5__H__‐thiazolo [5,4‐__e__][