## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Synthesis of Aminoethyl Glycoside of the Oligosaccharide Chain of Ganglioside Fuc-GM1.
β Scribed by P. E. Cheshev; Yu. E. Tsvetkov; N. E. Nifantiev
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The pseudo tetrasaccharide 2 was designed to mimic diol 3 was enantioselectively synthesized by an asymmetric Diels-Alder reaction, followed by dihydroxylation of the ganglioside GM1, the membrane receptor of both the cholera toxin and of the heat-labile toxin of E. coli. Compound 2 resulting cycloh
Glycosidation of the lactose derivative 4 with [1-13 C]-sialyl sialic acid gave the trisaccharide 5 which was transformed into [1c-13 C]-GM 3 ([1c-13 C]-1). xanthate 3, prepared from enzymatically obtained [1-13 C]-FULL PAPER Scheme 2 Reagents and conditions: (a) PST, AgOTf, CH 3 CN/CH 2 Cl 2 , Οͺ70Β°
## Abstract The enkephalins are endogenous neurotransmitters and bind with high affinity at the Ξ΄βreceptor. Gangliosides, the major glycans of nerve cells, known to interact both with receptors and ligands on the cell surface, have been implicated to modulate the actions of opioid receptors by allo
## Abstract __Two metabolically engineered__ Escherichia coli __strains have been constructed to produce the carbohydrate moieties of gangliosides GM2 (GalNAc__Ξ²__β4(NeuAc__Ξ±__β3)Gal__Ξ²__β4Glc; Gal=galactose, Glc=glucose, Ac=acetyl) and GM1 (Gal__Ξ²__β3GalNAc__Ξ²__β4(NeuAc__Ξ±__β3)Gal__Ξ²__β4Glc. The G