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ChemInform Abstract: A Total Synthesis of the Methyl Glycoside of Ganglioside GM1.

✍ Scribed by Samit K. Bhattacharya; Samuel J. Danishefsky

Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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Synthesis of a Pseudo Tetrasaccharide Mi
Synthesis of a Pseudo Tetrasaccharide Mimic of Ganglioside GM1
✍ Anna Bernardi; Giovanna Boschin; Anna Checchia; Maria Lattanzio; Leonardo Manzon πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 305 KB πŸ‘ 1 views

The pseudo tetrasaccharide 2 was designed to mimic diol 3 was enantioselectively synthesized by an asymmetric Diels-Alder reaction, followed by dihydroxylation of the ganglioside GM1, the membrane receptor of both the cholera toxin and of the heat-labile toxin of E. coli. Compound 2 resulting cycloh