Synthesis of ฮฑ-amino acid derivatives by
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C. Cardellicchio; V. Fiandanese; G. Marchese; F. Naso; L. Ronzini
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Article
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1985
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Elsevier Science
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French
โ 221 KB
The reactions of Grignard reagents with methyl 2-acetamidoacrylate in the presente of CuI give fair to good yields of cr-amino esters; the corresponding a-deutero-or a-methyl-derivatives are obtained upon quenching with D+ or CH31, respectively.