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Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction

✍ Scribed by Evans, Gary B.; Furneaux, Richard H.; Tyler, Peter C.; Schramm, Vern L.

Book ID: 120022680
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 36 KB
Volume: 5
Category: Article
ISSN: 1523-7060
DOI: 10.1021/ol035293q

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Synthesis of a Transition State Analogue

Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase via the Mannich Reaction.

✍ Gary B. Evans; Richard H. Furneaux; Peter C. Tyler; Vern L. Schramm 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 111 KB 👁 1 views

Synthesis of Transition State Analogue I

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

✍ Gary B. Evans; Richard H. Furneaux; Graeme J. Gainsford; Vern L. Schramm; Peter 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 314 KB

AbstractÐSyntheses of the `Immucillins', potent aza-C-nucleoside inhibitors of purine nucleoside phosphorylase are reported as well as those of 5-deoxy-, 5-deoxy¯uoro-and 2-deoxy-analogues and others having modi®ed bases.

Synthesis of Second-Generation Transitio

Synthesis of Second-Generation Transition State Analogues of Human Purine Nucleoside Phosphorylase

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l -Enantiomers of Transition State Analo

l -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

✍ Rinaldo-Matthis, Agnes; Murkin, Andrew S.; Ramagopal, Udupi A.; Clinch, Keith; M 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 221 KB

8-Aza-immucillins as Transition-State An

8-Aza-immucillins as Transition-State Analogue Inhibitors of Purine Nucleoside Phosphorylase and Nucleoside Hydrolases

✍ Evans, Gary B.; Furneaux, Richard H.; Gainsford, Graeme J.; Hanson, John C.; Kic 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 109 KB

ChemInform Abstract: Synthesis of Transi

ChemInform Abstract: Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases.

✍ Gary B. Evans; Richard H. Furneaux; Graeme J. Gainsford; Vern L. Schramm; Peter 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v