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Synthesis of a novel tetracyclic azaindolo[2,1-c][1,4]benzoxazine ring system

✍ Scribed by Santosh Kurhade; Rahul D. Kaduskar; Bhavesh Dave; Parimi Atchuta Ramaiah; Venkata P. Palle; Debnath Bhuniya

Book ID
104098940
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
580 KB
Volume
52
Category
Article
ISSN
0040-4039

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A convenient synthesis of pyrrolo[2,1-c]
A convenient synthesis of pyrrolo[2,1-c][1,4] benzoxazines
✍ Isabel SΓ‘nchez; Maria Dolors Pujol πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 417 KB

The pyrrolo [2,l-c][1,4]benzoxazine system was synthesized from 2-fluoroaniline involving an intramolecular nucleophilic displacement of the fluoride atom. The intermediate alcohols 7a and 10 were treated in basic media under strictly controlled conditions which led to the desired tricyclic structur