A convenient synthesis of pyrrolo[2,1-c]
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Isabel SΓ‘nchez; Maria Dolors Pujol
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Article
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1999
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Elsevier Science
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French
β 417 KB
The pyrrolo [2,l-c][1,4]benzoxazine system was synthesized from 2-fluoroaniline involving an intramolecular nucleophilic displacement of the fluoride atom. The intermediate alcohols 7a and 10 were treated in basic media under strictly controlled conditions which led to the desired tricyclic structur