𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of a nonpeptide carbon-11 labeled substance P antagonist for PET studies

✍ Scribed by Del Rosario, Renato B.; Mangner, Thomas J.; Gildersleeve, David L.; Shreve, Paul D.; Wieland, Donald M.; Lowe, John A.; Drozda, Susan E.; Snider, R.Michael


Book ID
122358879
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
263 KB
Volume
20
Category
Article
ISSN
0969-8051

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Carbon-14 labeling of a trifluoromethoxy
✍ Conrad E. Raab; Dennis C. Dean; David G. Melillo 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 149 KB

## Abstract Synthesis of a carbon‐14 labeled trifluoromethoxy group has been accomplished using the stepwise oxidative fluorination–desulfurization of a readily prepared [^14^C]xanthate (**5**). This novel labeling procedure allowed a rapid synthesis of substance P antagonist candidate **1** that a

Synthesis of 11C-labelled acamprosate fo
✍ Jan Courtyn; Patrick Goethals; Johan Van der Eycken; Richard Dams 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 104 KB

## Abstract A method for labelling acamprosate (calcium __N__‐acetyl homotaurinate), an anti‐craving compound for ethanol, with ^11^C, has been developed for __in vivo__ studies with positron emission tomography (PET). The synthesis was based on the acylation of homotaurinate using [^11^C]acetyl ch

Carbon-11 labeling of a potent, nonpepti
✍ William B. Mathews; H. Donald Burns; Robert F. Dannals; Hayden T. Ravert; Elizab 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 415 KB 👁 1 views

## Abstract [α‐^11^C]Benzoyl chloride was synthesized and purified by normal phase HPLC. [^11^C]MK‐996 ([^11^C]__N__‐[[4′[(2‐ethyl‐5,7‐dimethyl‐3H‐imidazo [4,5‐b]pyridin‐3‐yl)methyl][1,1′‐biphenyl]‐2‐yl]sulfonyl]‐benzamide), a potent and selective ligand for the AT~1~ receptor, was prepared by __N_