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Synthesis of a 11C-labeled NK1 receptor ligand for PET studies

✍ Scribed by E. Livni; John W. Babich; Manoj C. Desai; Dennis M. Godek; Robert A. Wilkinson; Robert H. Rubin; Alan J. Fischman

Book ID
116171976
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
624 KB
Volume
22
Category
Article
ISSN
0969-8051

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✍ Jan Courtyn; Patrick Goethals; Johan Van der Eycken; Richard Dams πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 104 KB

## Abstract A method for labelling acamprosate (calcium __N__‐acetyl homotaurinate), an anti‐craving compound for ethanol, with ^11^C, has been developed for __in vivo__ studies with positron emission tomography (PET). The synthesis was based on the acylation of homotaurinate using [^11^C]acetyl ch