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Synthesis of a new series of potent inhibitors of thromboxane A2 biosynthesis

✍ Scribed by E.J. Corey; Stephen G. Pyne; Andrew I. Schafer

Publisher: Elsevier Science
Year: 1983
Tongue: French
Weight: 206 KB
Volume: 24
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)86251-6

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✦ Synopsis

The pyridino prostanoids 2, 12 and lfl have been synthesized (in racemic form) and have been found to be effective inhibitors of the biosynthesis of thromboxane A2 in human platelets QC,, l-3 PM).

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