Synthesis of a New Series of Imidazo[1,5-d]pyrido[2,3-b][1,4]thiazines as Potential Ligands for the GABA Receptor Complex.
✍ Scribed by Manuela Weber; Thomas Erker
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 94 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A facile synthesis of the imidazo[1,5‐__d__]thieno[2,3‐__b__][1,4]thiazine ring system is described. Reaction of 6‐benzyl‐2,3‐dihydro‐1__H__‐thieno[2,3‐__b__][1,4]thiazine‐2‐one (**1**) with potassium __tert__‐butoxide and diethylchlorophosphate gave intermediate **2** which resulted in
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract A new series of 3‐[ω‐[4‐(4‐substituted phenyl)piperazin‐1‐yl]alkyl]‐5__H__‐pyrimido[5,4‐__b__]indole‐(1__H__,3__H__)‐2,4‐diones (**3–10** and **12–13**) were synthesized from the __N__‐(2‐chloroethyl)‐__N'__‐[3‐(2‐ethoxycarbonyl)indolyl] urea (**1**) or the __N__‐(3‐chloropropyl)‐__N'__