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ChemInform Abstract: Synthesis of Novel 5H-Pyrimido[5,4-b]indole-(1H,3H)2,4-diones as Potential Ligands for the Cloned α1-Adrenoceptor Subtypes.

✍ Scribed by G. Romeo; F. Russo; A. De Blasi

Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Facile Synthesis of
ChemInform Abstract: Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5-b][1,4]diazepine-2,4(1H,3H)-diones.
✍ Shahriyar Taghavi-Moghadam; Ruediger Stumpf; Helmut Fischer; Wolfgang Pfleiderer 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

## Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5b][1,4]diazepine-2,4(1H,3H)-diones. -A new approach to the regioselective synthesis of the title compounds (IV) starting from readily accessible 6-amino-5-benzylideneaminopyrimidines (I) is described. Condensation of compound (I) with diet