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Synthesis of a Naphthyridone p38 MAP Kinase Inhibitor

✍ Scribed by Chung, John Y. L.; Cvetovich, Raymond J.; McLaughlin, Mark; Amato, Joseph; Tsay, Fuh-Rong; Jensen, Mark; Weissman, Steve; Zewge, Daniel


Book ID
120242391
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
253 KB
Volume
71
Category
Article
ISSN
0022-3263

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Synthesis of RWJ 68354: A potent inhibit
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The regiospecific synthesis of RWJ 68354, a potent inhibitor of the p38 MAP kinase, via a variation oft,he Bischler-M6hlau indole synthesis is reported.