𝔖 Bobbio Scriptorium
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Synthesis of a Mevinic Acid Lactone Precursor

✍ Scribed by Mash, Eugene A.; Arterburn, Jeffrey B.; Nimkar, Sandeep K.


Book ID
120957353
Publisher
Taylor and Francis Group
Year
1992
Tongue
English
Weight
489 KB
Volume
11
Category
Article
ISSN
0732-8303

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## Abstract Total synthesis of mevinic acid analog **1** has been achieved efficiently starting from chiral 2,3‐__O__‐isopropylidene‐D‐glyceraldehyde (**2**). The synthesis involves __Mitsunobu__ reaction and __Evans__' intramolecular oxa‐__Michael syn__‐addition reactions as key steps.