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Total Synthesis of a Mevinic Acid Analog

✍ Scribed by Thummalapally Srikanth Reddy; Dorigondla Kumar Reddy; Manchala Narasimhulu; Dasari Ramesh; Yenamandra Venkateswarlu

Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
152 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Total synthesis of mevinic acid analog 1 has been achieved efficiently starting from chiral 2,3‐O‐isopropylidene‐D‐glyceraldehyde (2). The synthesis involves Mitsunobu reaction and Evans' intramolecular oxa‐Michael syn‐addition reactions as key steps.

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