## Abstract Rational conformation design led us to a synthesis of the __Ο__βamidoβundecenamide **4**, which was shown by theoretical means (simulated annealing techniques) and by NMR and IR spectroscopy to have a high tendency to populate a conformation corresponding to a natural __Ξ²__βIIβ²βtype hai
Synthesis of a conformationally restricted DNA hairpin
β Scribed by Glick, Gary D.
- Book ID
- 126802381
- Publisher
- American Chemical Society
- Year
- 1991
- Tongue
- English
- Weight
- 288 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A conformationally constrained analogue of the paclitaxel side-chain was synthesised in an enantioselective way from ethyl IH-indene-2-carboxylate. Coupling with 7-triethylsilylbaccatin III and deprotection afforded 2',2"-methylenepaclitaxel, a novel analogue of the natural product retaining antican
Abslrart: The synthesis of a new, conformationally restrained a~log of tryptoghan, 1,2,3,4ktrahydtv-2-ami-2-mrboxy\_cyflopentfbJindole (5) is descrhd. The key step involzm the BF3-Et,0 catalyzed intramolecular cycl&atian of adinoketone 2b into the lt3,4tetrahydro\_~~ (3). Conformationally restricted