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Synthesis of a conformationally constrained analogue of BW A78U, an anticonvulsant adenine derivative

✍ Scribed by Laurent Désaubry; Camille Georges Wermuth; Jean-Jacques Bourguignon

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
159 KB
Volume
36
Category
Article
ISSN
0040-4039

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Synthesis and anticonvulsant properties
Synthesis and anticonvulsant properties of BW A78U structurally-related compounds
✍ Laurent Désaubry; Camille G. Wermuth; Annie Boehrer; Christian Marescaux; Jean-J 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 234 KB

Several analogues of the anticonvulsant BW A78U 1 have been synthesized and tested for their anticonvulsant properties, providing preliminary data concerning the structural requirements for this family of drugs. Currently marketed antiepileptic drugs do not often provide complete control of seizure