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Synthesis and anticonvulsant properties of BW A78U structurally-related compounds

✍ Scribed by Laurent Désaubry; Camille G. Wermuth; Annie Boehrer; Christian Marescaux; Jean-Jacques Bourguignon

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
234 KB
Volume
5
Category
Article
ISSN
0960-894X

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✦ Synopsis

Several analogues of the anticonvulsant BW A78U 1 have been synthesized and tested for their anticonvulsant properties, providing preliminary data concerning the structural requirements for this family of drugs.

Currently marketed antiepileptic drugs do not often provide complete control of seizures and are associated with a wide range of side effects ~. Due to the need for better antiepileptic drugs, a program was initiated to discover and develop improved antiepileptic agents. The potent anticonvulsant purine BW A78U

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