๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

โœ Scribed by Rachel Brown; W.Ewen Smith; Duncan Graham

Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
177 KB
Volume
44
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles.

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of a benzotriazole phosphorami
Synthesis of a benzotriazole phosphoramidite for attachment of oligonucleotides to metal surfaces
โœ Rachel Brown; W.Ewen Smith; Duncan Graham ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 86 KB

A method for the addition of a benzotriazole moiety to the 5%-terminus of an oligonucleotide via phosphoramidite chemistry has been developed. Use of a monomethoxytrityl protecting group on the benzotriazole allowed fast on-column detritylation purification by reverse-phase HPLC. Surface enhanced Ra

The synthesis and first full structural
The synthesis and first full structural elucidation of a benzotriazole azo dye
โœ Duncan Graham; Alan R. Kennedy; Simon J. Teat ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 256 KB

## Abstract Although azo dyes containing benzotriazole are of interest as substrates for surface enhanced resonance Raman scattering, SERRS, little is known of their molecular structure due to their poor crystal growth properties. We recently synthesised a highly crystalline dihydroquinoline __via_

Synthesis of 14C-labelled bis-azo biphen
Synthesis of 14C-labelled bis-azo biphenyl dyes
โœ D. Franklin Milam; Robert K. Lynn ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 199 KB

Two 14C-label l e d bis-azo biphenyl dyes have been prepared from u n i f o r m l y r i n g -l a b e l l e d 14C-benzidine and 14C-3,3'dimethylbenzidine. The amines were t e t r a -a z o t i z e d w i t h sodium n i t r i t e and HCL. D i r e c t Blue 6 was then prepared from t e t r a -a z o benzid